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Reserch and Technologies

Scientific research and technological innovation in the nutraceutical sector

From pioneering research in cellular biology to precise preparation methods and advanced analytical techniques, we are dedicated to pushing the frontiers of nutraceutical science and creating effective, high-quality food supplements and medical devices.  

In our laboratories, we employ cutting-edge research models to drive scientific innovation. This translates into groundbreaking formulations that transform patented raw materials into safe, effective, and sophisticated products, tailored to address increasingly specific health needs.  

All scientific research and technology development activities are overseen by a structured Scientific Directorate, which is responsible for initiating and supervising new research projects, coordinating activities across both internal and external laboratories, and conducting rigorous safety and quality controls on raw materials and finished products. 

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Sucrosomial® Technology, a patent developed by PharmaNutra, enables the transport of micronutrients within a matrix of phospholipids and sucrose esters, ensuring superior tolerability and absorption in the body. This advanced delivery system not only protects essential nutrients like minerals, vitamins and plant extracts but also transports them to the intestine intact, where absorption takes place. Numerous clinical studies and foundational research have confirmed the exceptional efficacy of this patented system, which is, to date, the only fast, safe and well-tolerated oral formulation designed to address mineral and vitamin deficiencies, particularly iron deficiency.

The structure of the Sucrosome® is the real breakthrough

This three-layer protection, consisting of phospholipids and sucrose esters, encases the molecule, allowing it to pass through the gastric environment without interacting with acidic substances or mucous membranes. Once it reaches the intestine, the Sucrosome® binds to M cells, which transport it into the bloodstream, where the molecule is released and absorbed efficiently. 

 

Diciture figura   
MATRICE FOSFOLIPIDICA  PHOSPHOLIPID MATRIX 
PRINCIPIO FUNZIONALE  FUNCTIONAL PRINCIPLE 
FOSFATO TRICALCICO  TRICALCIUM PHOSPHATE 
MATRICE DI SUCRESTERE  SUCRESTER MATRIX 

Advantages of Sucrosomial® Technology

Better absorption

High tolerability

More effective, faster

Scientific validity

Patented technology

Sucrosomial® Technology, initially developed to address iron deficiency, has since been successfully applied to a range of essential minerals and vitamins, including iron, magnesium, zinc, selenium, iodine, calcium, chromium, vitamin D3 and vitamin B12. 

In all these applications, this innovative patent has proven invaluable not only in correcting both mild and severe nutritional deficiencies but also in preventing further complications and enhancing the quality of life of patients across various clinical fields, ranging from cardiology to gastroenterology, gynaecology to paediatrics, and even oncology and nephrology. 

A patented blend of plant-based fatty acids and cetyl alcohol, developed to improve joint function and movement capacity. The functional principle of Cetylated Fatty Acids (CFAs) was originally developed for topical formulations (Cetilar® r.m.) and later adapted into an oral version (Lipocet®, novel food). 

CFAs in topical formulations: a functional ingredient for restoring musculoskeletal mobility

Cetylated Fatty Acids (CFAs) are able to quickly and effectively penetrate the skin barrier, which is normally impermeable to many active ingredients on the market. Due to their small molecular size and fat-soluble nature, they have an exceptionally high absorption rate, enabling the active ingredient to reach concentrations as high as 7.5%. 

This patented mechanism not only helps restore the functionality of damaged membranes but also provides rapid relief from joint and musculoskeletal pain.  

Diciture in figura   
CFA  CFA 
MEMBRANA CELLULARE  CELL MEMBRANE 

 

Cetylated Fatty Acids in oral formulations: supporting joint physiology

In 2022, PharmaNutra's research led to the patent for Lipocet®, an innovative food supplement based on a blend of Cetylated Fatty Acids (CFAs). The classification of CFAs as Novel Food marks a significant milestone in the development of new oral solutions, expanding beyond topical applications to support muscle and joint well-being. 

CFA-based food supplements are an exclusive offering from PharmaNutra and represent a fresh approach to treating musculoskeletal issues which focuses on restoring functionality and mobility rather than merely on reducing pain. 

The research underlying the development of our pharmaceutical and nutraceutical technologies.  In our molecular biology laboratory, we carry out fundamental projects for the progress of nutritional research, making groundbreaking discoveries that pave the way for medical innovations and the development of more effective treatments.

Scientific collaborations with leading Italian and international universities and research centres have always been a cornerstone of PharmaNutra's growth.   Over the years, we have initiated numerous research projects with prestigious institutions, including La Sapienza University of Rome, the University of Brescia, the Paediatric and Adolescent Andrology Foundation, and the University of Pisa. 

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Our Quality Control system ensures that each food supplement and medical device is synonymous with reliability, innovation and superior quality.  PharmaNutra is certified to ISO 9001 and SA 8000 standards, which regulate quality management and corporate social responsibility respectively.  Additionally, our products have earned the CE Mark, awarded by the ISS for class IIA medical devices, and the Play Sure Doping Free seal, issued by Doping Free S.A. and the No Doping Life association, after rigorous testing by Bureau Veritas Italia S.p.A. 

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